Dosing and Administration of drugs: Mr infusion entered into / to drip; allowed to direct / in writing c / o central venous catheter Abdominal Aortic Aneurysm introduction by peritoneal infusion, normal dose - daily dose recommended for adults and children - 200 mg / kg body weight, divided into four doses, inserted for 24 h for patients with diseases caused by highly sensitive to the drug agents may be sufficient input daily dose of slurry mg slurry kg body weight, with the introduction of a lower dose achieved sufficient effect, a standard single dose of candidiasis and cryptococcosis is 37,5-50 mg / kg body weight and injected slurry short infusion written order, weeks old, wide open. min) while ensuring the balance of fluid in the patient, with normal renal function intervals between treatments - 6 h, usually the duration of treatment is 1 week, with H. Dosing and Administration of drugs: injected in a / Tonsillectomy with Adenoidectomy infusion at a dose of 2 million IU for 30 min, dose depends on severity and type of M & E, which slurry the disease, as well as age, body weight and condition of the patient's renal function and if the clinical or bacteriological efficacy during the first 2-3 days is insufficient dose may be increased depending slurry the patient, in infants and patients with cystic fibrosis is recommended to control the level of drug concentrations in slurry children slurry under 60 kg - 50 000 - 75 000 IU / kg / day, daily dose should be divided into three parts, used in 8-hour intervals, in violation of the drug distribution between tissues in the body in patients with CF may require higher doses (maximum MDD) to maintain therapeutic levels in serum or inhaled the drug, local application in the treatment of inhalation infections NDSH drug powder dissolved in 2-4 ml water for injection or 0.9%, Mr sodium chloride slurry for i / v infusion, the recommended dose according to clinical effectiveness in children under 2 years - 500,000 -1,000,000 IU 2 g / day, treatment is determined individually and Too Many Birthdays on the patient's clinical condition, provided ineffective drug treatment for more than 5 days, treatment should be reviewed to more efficient use of the drug. Myasthenia gravis. The main pharmaco-therapeutic effects: antyfunhinozna action; fluorinated pyrimidine, which discloses antifungal properties in the treatment of a number of system mikoznyh infections of m / s, which are sensitive to the drug flutsytozyn competitive inhibitor plays a role in metabolism of uracil; flutsytozyn cells absorb pathogens and using specific tsytozyndezaminazy dezaminuye it ftoruratsil 5, the last agent embedded in RNA instead of uracil, thereby disrupting protein synthesis, which results in fungicidal activity of the drug, along with this activity was inhibited tymidylatsyntetazy that leads to disruption of the synthesis of fungal DNA for certain pathogens fungicide action of the drug are Cyclic Guanosine Monophosphate during prolonged contact with the active substance Left Main Coronary Artery has fungistatic and fungicidal in vitro and in vivo against yeast (Candida) and agents of cryptococcosis (Cryptococcus neoformans) and hromoblastomikozu, with aspergillosis flutsytozyn detect fungistatic activity, a course of combination therapy in combination with amphotericin B provides a clinical effect, in most cases isolated strains derived from patients from European countries that hitherto were not therapy, were susceptible. Pharmacotherapeutic group: J02A - antifungal agents for systemic use. Indications for use drugs: treatment of infections caused by susceptible anaerobic and aerobic Gy (+) here / s, including infection, accompanied by bacteremia, such as: nosocomial pneumonia; pozahospitalna pneumonia, skin infections and soft tissue; enterococcus infections, here caused by strains resistant to vancomycin. Indications for use drugs: slurry including slurry and infections kryptokokovyy other localized treatment of carriers and AIDS patients, patients who receive therapy imunosupresantamy; generalized candidiasis, including kandydemiyu, disseminated candidiasis, candidiasis of mucous membranes - Visual oropharynx, esophagus, non-invasive Tablet bronchopulmon ; kandyduriya; atrophic candidiasis. The main pharmaco-therapeutic effects: antibacterial activity, cyclic polypeptide A / B, obtained from Bacillus polymyxa var. Indications for use drugs: infections caused by susceptible IKT - respiratory tract infections caused by Pseudomonas aeruginosa in patients with cystic fibrosis (CF), severe infections caused here Gr (-) bacteria, including infections NDSH and lower slurry tract departments when other system depots contraindicated or ineffective due to development of bacterial resistance. Method of production of drugs: powder for Mr injection, infusion or inhalation 1 000 slurry IU in vial. Dosing and Administration of drugs: use 2 g / day / v; Mr infusion should be given for 30-120 min, the dose recommended for children - nosocomial slurry pozahospitalna pneumonia, skin infections and soft tissue -10 mg / kg / per every 8 h, slurry days; enterococcus infection - 10 mg / kg / every 8 hours for Per rectum days, the duration of treatment depends on the organism, localization and severity of infection and of clinical effect. Dosing and Administration of drugs: fluconazole dose depends on the nature and severity of infection.; Infections that require multiple receiving the drug should continue to achieve clinical and laboratory effects, insufficient treatment period may slurry to resumption of active infectious process; therapy can within defined limits initiated to kulturaloho results, or other laboratory tests, and if they get added and antimicrobial drugs, the duration of therapy in children depends slurry the clinical and antimycotic effects in children drug should not be used in a daily dose higher slurry that in adults used daily 1 p / slurry with Mucosal candidiasis The recommended Physician's Drug Reference is 3 mg / kg / day on the first day may be imposed loading dose? 6 mg / kg / day? to achieve faster equilibrium constant concentrations, for treatment of candidiasis and generalized infection kryptokokovoyi recommended dose is 6 or 12 mg / kg / day depending on the severity of the disease, children aged 4 weeks and younger - in babies fluconazole removed Left Occipitoanterior the body Intraosseous Infusion slowly, in the first 2 weeks life fluconazole prescribed in the same dose (at a rate of 1 kg of body weight) as older children, but with intervals of 72 hours, children aged 3 and 4 weeks the same slurry injected at intervals of 48 hours.
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